We take a brief look at Saturday's opponents...Two years ago, this fixture was a League One encounter, but both clubs have gained promotion to the Championship via the playoffs over the past couple of seasons.
While Rotherham have played at this level for 18 months, Preston North End are still acclimatising to life in the second tier.
They come into the first game of 2016 on the back of an impressive 1-0 victory over promotion hopefuls Hull City though and lie in 17th place - seven points clear of the drop zone.
A win for Neil Redfearn's side will take Rotherham to within four points of the Lancashire outfit, while Preston could move into the top half of the Championship with a win.
• Division One: 1889, 1890
• FA Cup: 1889, 1938
One to watch – Daniel Johnson
23-year-old Daniel Johnson is approaching his first anniversary at Preston and he has quickly become a fan favourite at Deepdale.
The midfielder arrived for just £50,000 from Aston Villa in January 2015 and made an immediate impact with eight goals in the second half of the campaign.
He's already netted seven goals in all competitions this season and has quickly become an important cog in Simon Grayson's side.
Although August's league encounter ended in a scoreless draw, Rotherham have happy memories of clashes with Preston from the 2014 League One playoff semi-finals.
Alex Revell's sublime solo goal in the first leg gave the Millers a 1-1 draw to take into the home tie a few days later. Despite falling behind to an early free kick from Paul Gallagher, strikes from Wes Thomas, Lee Frecklington and Kieran Agard saw us reach the final. The rest, as they say, is history!
Pickford; Vermijl, Wright, Huntington, Cunningham; Gallagher, Welsh, Johnson, Reach; Keane, Garner